Endocrinology

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PILAR · THE ARSENAL

Endocrinology

Hormones are the body's electrical wiring. A dysregulated axis destroys sleep, strength, libido, cognition, and body composition. Conventional medicine optimizes for "laboratory ranges"; we optimize for functional physiology.

Why it matters

The HPT (thyroid), HPG (gonadal), and HPA (cortisol) axes determine most of the vague symptoms of aging: fatigue, brain fog, loss of lean mass, low libido, and poor sleep. Insulin resistance—measured by HOMA-IR—is the most prevalent and most underdiagnosed endocrine dysfunction in the modern world.

Biomarkers we monitor

  • Thyroid: TSH 0.5-2.0 mUI/L, free T3 in upper third, free T4 in upper half, negative anti-TPO/anti-Tg, low reverse T3.
  • gonadal axis in men: total testosterone >500 ng/dL, free >20 pg/mL, SHBG, estradiol, DHT.
  • female gonadal axis: estradiol, luteal phase progesterone, DHEA-S, total and free testosterone, SHBG.
  • Insulin and glucose: HOMA-IR <1.5; fasting insulin <5 µUI/mL; HbA1c <5.4%.
  • Cortisol: diurnal rhythm (saliva 4 points), not just morning.
  • Vitamin D 25-OH: 40-60 ng/mL.

Non-negotiable levers

  • Dream and light: The aligned circadian rhythm regulates almost the entire hormonal cascade.
  • Heavy force: It sensitizes to insulin and elevates the somatotropic axis.
  • Body composition: Low visceral fat = minimal aromatization and insulin resistance.
  • Disruptors: Minimize BPA, phthalates, parabens; audit water, plastics and cosmetics.

What we audit

Thyroid support (selenium, dosed iodine, zinc), natural gonadal support (zinc, boron, vitamin D, evidence-based ashwagandha), insulin sensitizers (berberine, myo-inositol, magnesium), and endocrine disruptor-free materials.

Minimum stack: full annual hormonal panel + correction of behavioral levers before pharmacology.

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