{"id":907,"date":"2026-06-14T22:31:00","date_gmt":"2026-06-14T22:31:00","guid":{"rendered":"https:\/\/menteymanzana.com\/?p=907"},"modified":"2026-06-14T22:31:00","modified_gmt":"2026-06-14T22:31:00","slug":"vitamina-d-anatomia-de-una-carencia","status":"publish","type":"post","link":"https:\/\/menteymanzana.com\/en\/vitamina-d-anatomia-de-una-carencia\/","title":{"rendered":"Vitamin D: Anatomy of a Deficiency"},"content":{"rendered":"<style>\nbody.postid-907>.wp-site-blocks>main.wp-block-group{display:none!important}\nbody.postid-907 .wp-site-blocks>.wp-block-group.has-global-padding{padding-top:0!important}\nbody.postid-907 .wp-site-blocks>.wp-block-group>.wp-block-group:first-child{padding-top:0!important;margin-top:0!important}\nbody.postid-907 .entry-title{display:none!important}\nbody.postid-907 .wp-block-post-title{display:none!important}\nbody.postid-907 main{padding-top:0!important}\nbody.postid-907 .post-thumbnail,body.postid-907 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em{color:#cccccc}\n\n@media(max-width:680px){\n  body.postid-907 h1.mm-custom-title{font-size:1.55em}\n  body.postid-907 .mm-subtitle{font-size:.9em}\n  body.postid-907 .mm-content h2{font-size:1.3em}\n  body.postid-907 .mm-content h3{font-size:1.1em}\n  body.postid-907 .mm-content p{font-size:.95rem}\n  body.postid-907 .mm-content table{font-size:.78rem}\n  body.postid-907 .mm-content table th,body.postid-907 .mm-content table td{padding:.45rem .55rem}\n}\n<\/style>\n\n<div class=\"mm-hero\"><img decoding=\"async\" src=\"https:\/\/menteymanzana.com\/wp-content\/uploads\/2026\/06\/vitamina-d-01-hero.png\" alt=\"C\u00e1psula de vitamina D y un sol de lat\u00f3n en una balanza antigua\" \/><\/div>\n\n<h1 class=\"mm-custom-title\"><span class=\"accent\">VITAMIN D<\/span>: ANATOMY OF A <span class=\"accent\">LACK<\/span><\/h1>\n<p class=\"mm-subtitle\">Metabolism, the silent deficiency in Mexico and evidence-based supplementation<\/p>\n\n<div class=\"mm-content\">\n\n<div class=\"mm-disclaimer\"><strong>Editorial note.<\/strong> This dossier is a review of clinical, pharmacological and nutritional epidemiology literature. <strong>This does not constitute medical advice or an invitation to self-medication.<\/strong> Vitamin D supplementation\u2014especially at high doses\u2014can interact with medications and certain conditions (kidney disease, sarcoidosis, hyperparathyroidism), so it should be guided by a blood 25(OH)D test and professional supervision. Recommended intakes from organizations such as the <strong>NIH<\/strong> and the <strong>IMSS<\/strong> They remain valid. The purpose is to rigorously document the metabolism of this prohormone, the magnitude of the deficiency in Mexico, and the criteria for safe correction.<\/div>\n\n<p>Vitamin D is often misnamed. Strictly speaking, it&#039;s not a vitamin: it&#039;s a <strong>prohormone<\/strong> which the body itself produces when the skin is exposed to sunlight, and whose receptors appear in almost all tissues. Therefore, its role goes far beyond the old headline of &quot;fixing calcium in bones&quot;: it participates in the immune response, muscle function, the regulation of inflammation, and cardiovascular and metabolic risk.<\/p>\n\n<p>The paradox explored in these pages is, above all, geographical. Mexico receives sunshine almost year-round; one might expect vitamin D deficiency to be a clinical rarity. Data from national surveys tell the exact opposite: the deficiency behaves like a silent pandemic, hitting hardest precisely where it&#039;s least expected. The intuition\u2014&quot;if there&#039;s sun, there&#039;s vitamin D&quot;\u2014turns out to be a poor representation of reality.<\/p>\n\n<p>This document reconstructs, with the available evidence, five questions: what is vitamin D and how is it activated, why its correct measurement matters so much, how widespread is the deficiency in the country, why modern supplementation no longer uses D3 alone, and where is the boundary between safely correcting and doing harm.<\/p>\n\n<div class=\"mm-callout\"><strong>The essentials in three lines.<\/strong> Vitamin D is a prohormone that is assessed by measuring 25-hydroxyvitamin D in the blood, not the active hormone. In Mexico, approximately <strong>78%<\/strong> Women of reproductive age do not reach sufficient levels of vitamin D3 despite abundant sunlight. Correcting this deficiency safely requires individualized dosages and, increasingly, supplementing vitamin D3 with magnesium and vitamin K2.<\/div>\n\n<h2>Module 1 \u2014 What vitamin D really is (and why it is measured in the blood)<\/h2>\n<figure class=\"mm-section-img\"><img decoding=\"async\" src=\"https:\/\/menteymanzana.com\/wp-content\/uploads\/2026\/06\/vitamina-d-02-modulo1-biologia.png\" alt=\"Visualizaci\u00f3n de la activaci\u00f3n de la vitamina D en el organismo\" \/><figcaption>Vitamin D is born inactive: it needs two &quot;activations&quot;, one in the liver and one in the kidney.<\/figcaption><\/figure>\n\n<h3>From the sun to the active hormone: a two-step chain<\/h3>\n<p>It all starts in the skin. Ultraviolet B (UVB) radiation transforms a cholesterol precursor into <strong>vitamin D3 (cholecalciferol)<\/strong>. Herein lies the first uncomfortable nuance: melanin acts as a natural sunscreen. According to the Fitzpatrick skin type scale, darker skin tones need more sun protection. <span class=\"mm-keyfig\">much longer periods of sunshine<\/span> to produce the same amount as fair skin. It&#039;s not an aesthetic detail, but a biological determinant of who falls short.<\/p>\n<p>But that D3 is still useless: it&#039;s inactive. It goes through two transformations. First the <strong>liver<\/strong> converts it into 25-hydroxyvitamin D, called <em>calcifediol<\/em>. Then the <strong>kidney<\/strong>, governed by parathyroid hormone (PTH), converts it into <em>calcitriol<\/em>, the truly active form. It&#039;s worth remembering this chain\u2014skin, liver, kidney\u2014because it explains almost everything that follows.<\/p>\n\n<h3>D2 versus D3: they are not interchangeable<\/h3>\n<p>Two forms coexist on the counter. Ergocalciferol (vitamin <strong>D2<\/strong>, (of plant or fungal origin) and cholecalciferol (vitamin <strong>D3<\/strong>, (of animal origin or, in vegan formulas, from lichens and microalgae). The evidence is compelling: the <strong>D3 lifts and supports better<\/strong> Blood levels are higher because it binds more strongly to its transport protein and remains in circulation longer. It is currently the standard for replenishing reserves.<\/p>\n\n<h3>Why is 25(OH)D measured and not the active hormone?<\/h3>\n<p>It would seem logical to directly measure the active hormone, calcitriol. In practice, this is misleading. When reserves begin to decline, the body increases PTH, which accelerates the production of calcitriol from the few remaining reserves. The result is a laboratory trap: calcitriol can be released. <em>normal or even high<\/em> while the reservoirs are emptying. It&#039;s called <strong>secondary hyperparathyroidism<\/strong>. That is why the international consensus uses the <strong>25-hydroxyvitamin D (25(OH)D)<\/strong>, with a half-life of <span class=\"mm-keyfig\">15 to 30 days<\/span>, as the only reliable biomarker of royal status.<\/p>\n<p>Clinical thresholds that guide the diagnosis are built upon this marker:<\/p>\n\n<table>\n<thead><tr><th>Classification<\/th><th>25(OH)D (ng\/mL)<\/th><th>Equivalent (nmol\/L)<\/th><th>What does it mean<\/th><\/tr><\/thead>\n<tbody>\n<tr><td><strong>Deficiency \/ lack<\/strong><\/td><td>Less than 20<\/td><td>Less than 50<\/td><td>Severely impaired calcium absorption. Risk of rickets, osteomalacia, secondary hyperparathyroidism, and myopathy.<\/td><\/tr>\n<tr><td><strong>Insufficiency<\/strong><\/td><td>20 to 30<\/td><td>51 to 75<\/td><td>Sustained suboptimal state. Slow loss of bone density and increased susceptibility to infections.<\/td><\/tr>\n<tr><td><strong>Sufficiency \/ optimal<\/strong><\/td><td>More than 30<\/td><td>More than 75<\/td><td>Therapeutic objective. Calcium absorption of 30 to 40% and improved muscle and bone health.<\/td><\/tr>\n<tr><td><strong>Potential toxicity<\/strong><\/td><td>More than 100<\/td><td>More than 250<\/td><td>Increased risk of hypercalcemia, kidney stones, and vascular damage.<\/td><\/tr>\n<\/tbody>\n<\/table>\n\n<h2>Module 2 \u2014 The Mexican Paradox<\/h2>\n<figure class=\"mm-section-img\"><img decoding=\"async\" src=\"https:\/\/menteymanzana.com\/wp-content\/uploads\/2026\/06\/vitamina-d-03-modulo2-paradoja.png\" alt=\"Metr\u00f3poli mexicana al atardecer con calles en sombra vistas desde una ventana\" \/><figcaption>A country with plenty of sunshine and yet a massive deficit: the urban indoor life explains it.<\/figcaption><\/figure>\n\n<h3>A sunny country, yet still running a deficit<\/h3>\n<p>The <strong>National Health and Nutrition Survey (ENSANUT) 2018-2019<\/strong> analyzed <span class=\"mm-keyfig\">1,262 women<\/span> From 20 to 49 years old, a sample representing more than 25 million people. The result shattered any optimism: <span class=\"mm-keyfig\">46.1% with insufficiency<\/span> y <span class=\"mm-keyfig\">31.6% with frank deficiency<\/span>. Added together, close to <span class=\"mm-keyfig\">77.7%<\/span> It did not reach the sufficiency threshold. Compared to the combined 86.6% of the 2012 ENSANUT survey, the improvement is barely marginal: the problem remains endemic.<\/p>\n\n<h3>The social paradoxes of the deficit<\/h3>\n<p>Breaking down the data reveals something counterintuitive. The deficiency is <strong>higher in the city than in the countryside<\/strong>Vertical architecture, indoor workdays, and pollution that scatters UVB radiation reduce skin synthesis. And there&#039;s an income paradox: the highest economic stratum exhibits the <strong>elderly<\/strong> The deficiency rate is higher among the poorest segments of the population, while the lowest-income group registers the lowest. The explanation is not mysterious: closed offices, commutes by car, and rigorous use of sunscreen keep those who can afford it out of the sun.<\/p>\n\n<table>\n<thead><tr><th>Stratum<\/th><th>Insufficiency<\/th><th>Deficiency<\/th><th>Reading<\/th><\/tr><\/thead>\n<tbody>\n<tr><td><strong>Urban<\/strong><\/td><td>47.2%<\/td><td>34.4%<\/td><td>Indoor life and smog that filters UVB.<\/td><\/tr>\n<tr><td><strong>Rural<\/strong><\/td><td>42.2%<\/td><td>21.2%<\/td><td>Working outdoors and enjoying clearer skies.<\/td><\/tr>\n<tr><td><strong>Low income<\/strong><\/td><td>46.0%<\/td><td>18.9%<\/td><td>Outdoor manual labor, public transport.<\/td><\/tr>\n<tr><td><strong>High income<\/strong><\/td><td>43.7%<\/td><td>41.3%<\/td><td>Office, closed car and strict photoprotection.<\/td><\/tr>\n<tr><td><strong>Northern Region<\/strong><\/td><td>50.2%<\/td><td>29.3%<\/td><td>Extreme weather that pushes people to use air-conditioned indoors.<\/td><\/tr>\n<tr><td><strong>Central Region<\/strong><\/td><td>44.4%<\/td><td>37.7%<\/td><td>The biggest obvious deficiency, associated with smog.<\/td><\/tr>\n<tr><td><strong>Southern Region<\/strong><\/td><td>46.3%<\/td><td>22.9%<\/td><td>Better relative status, less industrialized life.<\/td><\/tr>\n<\/tbody>\n<\/table>\n\n<h3>Body weight and sedentary lifestyle<\/h3>\n<p>Biological factors are also present in addition to environmental factors. <strong>obesity<\/strong> \u2014present in 39.71% of the sample\u2014 acts as an undesirable reservoir: because it is fat-soluble, vitamin D is sequestered in fatty tissue and is not released effectively into the bloodstream, perpetuating the deficiency. Meanwhile, moderate physical activity is protective, largely because it is usually performed outdoors.<\/p>\n\n<h3>Why the diet isn&#039;t enough<\/h3>\n<p>The intuitive answer would be \u201ceat better.\u201d The problem is that vitamin D is extremely rare in the food chain. The average intake of Mexican women is barely <span class=\"mm-keyfig\">2.56 \u00b5g\/day (about 102 IU)<\/span>, far from the recommended 400 to 600 IU. And meeting that quota with food alone is unfeasible: you would need approximately [number missing] every day. <em>26 sardines<\/em>, more than <em>13 eggs<\/em>, nearly <em>1.3 kg of liver<\/em> or almost <em>3 liters of milk<\/em> without fortification. The nutritional conclusion is clear: diet alone does not correct a clinical deficiency.<\/p>\n\n<h2>Module 3 \u2014 The metabolic trinity: D3, K2 and magnesium<\/h2>\n<figure class=\"mm-section-img\"><img decoding=\"async\" src=\"https:\/\/menteymanzana.com\/wp-content\/uploads\/2026\/06\/vitamina-d-04-modulo3-trinidad.png\" alt=\"Bodeg\u00f3n de c\u00e1psula de vitamina D3, c\u00e1psulas de K2 y cristales de magnesio\" \/><figcaption>Modern vitamin D doesn&#039;t travel alone: magnesium activates it and K2 directs calcium.<\/figcaption><\/figure>\n\n<h3>The D3 no longer travels alone<\/h3>\n<p>One of the most significant developments of the last decade is the refutation of vitamin D3 as a standalone therapy. Administering high doses of cholecalciferol as monotherapy for extended periods can not only be ineffective in some individuals but can also contribute to cardiovascular problems. Mechanistic evidence suggests that D3 should be viewed as part of a three-part network: it needs... <strong>magnesium<\/strong> y <strong>vitamin K2<\/strong> (in its menaquinone-7 or MK-7 form) to do its job well.<\/p>\n\n<h3>Magnesium: the switch that almost no one checks<\/h3>\n<p>The enzymes that &quot;switch on&quot; vitamin D in the liver and kidneys depend on magnesium as a cofactor. When this mineral is scarce\u2014a common occurrence due to depleted soils and ultra-processed diets\u2014supplementation may not work: the prohormone becomes stuck in its inactive forms, leading to a range of symptoms. <strong>\u201c&quot;endurance&quot;\u201d<\/strong> to vitamin D. Magnesium also stabilizes cellular ATP, improves insulin sensitivity, and moderates neuronal excitability.<\/p>\n\n<h3>Vitamin K2 (MK-7): the calcium transit director<\/h3>\n<p>Active D3 does one thing with enormous efficiency: it increases calcium absorption. What <em>No<\/em> What it knows how to do is decide where that calcium goes. Vitamin K2 fills that gap. MK-7 activates two key proteins: the <strong>osteocalcin<\/strong>, which anchors calcium in bone, and the <strong>matrix Gla protein (MGP)<\/strong>, which prevents calcium from depositing in the arteries. Without enough K2, high doses of D3 can accelerate the <strong>arterial calcification<\/strong>Calcium enters, but precipitates in the wrong place. The D3 + K2 synergy protects both the skeleton and the endothelium.<\/p>\n\n<h3>Cofactors and timing of intake<\/h3>\n<p>The picture is completed with two adjuvants: the <strong>zinc<\/strong> (immune defense, wound healing, and testosterone maintenance) and the <strong>naringin<\/strong>, A grapefruit flavonoid with effects on bone formation and vascular protection. And there&#039;s a simple chronobiological rule: since D3 and K2 are fat-soluble, they should be taken <strong>with a meal that has at least <span class=\"mm-keyfig\">10g of fat<\/span><\/strong>; Magnesium, due to its relaxing effect, is usually better tolerated at night.<\/p>\n\n<h2>Module 4 \u2014 Dosage, rescue and dangers<\/h2>\n<figure class=\"mm-section-img\"><img decoding=\"async\" src=\"https:\/\/menteymanzana.com\/wp-content\/uploads\/2026\/06\/vitamina-d-05-modulo4-dosis.png\" alt=\"Bodeg\u00f3n de farmacia con frasco \u00e1mbar, bl\u00edster y documento regulatorio\" \/><figcaption>Between correction and poisoning, the dose is important: that&#039;s why it&#039;s individualized and monitored.<\/figcaption><\/figure>\n\n<h3>Maintenance and rescue therapy<\/h3>\n<p>For a healthy person, the reference intake is around <span class=\"mm-keyfig\">600 IU\/day<\/span>, with a tolerable limit of 4,000 IU. But that quota, intended for prevention, is ineffective for <em>correct<\/em> an existing deficiency. High-risk groups\u2014older people, those with very dark skin, obesity, bariatric surgery, or intestinal malabsorption\u2014often require maintenance doses of <span class=\"mm-keyfig\">3,000 to 6,000 IU\/day<\/span>. In cases of severe deficiency (below 20 ng\/mL), the standardized rescue protocol is a macrodose of <span class=\"mm-keyfig\">50,000 IU weekly for 6 to 8 weeks<\/span>, This is followed by maintenance and monitoring of 25(OH)D levels each trimester. In pregnancies with documented deficiency, daily or bi-weekly regimens are used, always under close supervision.<\/p>\n\n<h3>Calcifediol: the powerful shortcut<\/h3>\n<p>There is an advanced alternative. <em>calcifediol<\/em> It already comes &quot;half activated&quot; (it skipped the hepatic step), so it is <span class=\"mm-keyfig\">3 to 6 times more powerful<\/span> and it acts faster than cholecalciferol. Precisely because of this potency, it is not for over-the-counter use: it can precipitate fulminant hypercalcemia. Its use is reserved for specialists and patients with severe renal or hepatic insufficiency, where the body&#039;s endogenous mechanisms no longer metabolize vitamin D3 effectively.<\/p>\n\n<h3>When correction causes harm<\/h3>\n<p>Hypervitaminosis D is real and iatrogenic: it appears after months of uncontrolled, disproportionate doses. Its mechanism is... <strong>hypercalcemia<\/strong>, with symptoms ranging from nausea, metallic taste, and fatigue to kidney stones, arrhythmias, and renal failure. It is contraindicated in primary hyperparathyroidism, hypercalcemia, severe renal insufficiency, and a history of kidney stones. The most treacherous scenario is the <strong>sarcoidosis<\/strong> and other granulomatous diseases: granulomas activate vitamin D without restraint, so that between the <span class=\"mm-keyfig\">47% and 64%<\/span> of these patients show a 25(OH)D <em>low<\/em> and misleading while calcitriol levels are toxically high. Blind supplementation in these cases can trigger severe hypercalcemia and kidney failure.<\/p>\n\n<h3>The Mexican market and the COFEPRIS framework<\/h3>\n<p>The <strong>COFEPRIS<\/strong> separates two worlds: the <em>medications<\/em> with health registration and the <em>dietary supplements<\/em>, These medications are prohibited from being claimed to have curative properties. In the prescription market, both finely titrated and megadosed products are available; in the over-the-counter market, there are easily accessible, high-volume formulations and the new generation of synergistic formulas.<\/p>\n\n<table>\n<thead><tr><th>Product \/ Category<\/th><th>Presentation<\/th><th>Typical use<\/th><\/tr><\/thead>\n<tbody>\n<tr><td><strong>Valmetrol-3<\/strong> (medicine)<\/td><td>200, 400, 800 and 1,600 IU<\/td><td>Fine titration; supervised pediatrics and geriatrics.<\/td><\/tr>\n<tr><td><strong>Histofil \/ D-Substitute<\/strong> (medicine)<\/td><td>4,000 IU dispersible<\/td><td>Rescue from chronic deficit and support in osteoporosis.<\/td><\/tr>\n<tr><td><strong>Hydroferol<\/strong> (medicine)<\/td><td>Calcifediol 0.266 mg<\/td><td>Specialist only (kidney or liver failure).<\/td><\/tr>\n<tr><td><strong>OTC shock<\/strong> (Simi D3, Pharmalife)<\/td><td>5,000 UI<\/td><td>Restocking over-the-counter products; without control, it increases the risk.<\/td><\/tr>\n<tr><td><strong>Premium formulas<\/strong> D3 + K2 + Mg<\/td><td>Capsules or gummies<\/td><td>Synergistic approach; it is advisable to verify the manufacturing quality.<\/td><\/tr>\n<\/tbody>\n<\/table>\n\n<p>The regulatory warning is significant: Mexican legislation on supplements allows for a flexibility that occasionally leads to harmful practices. COFEPRIS itself has issued alerts against products of unproven efficacy sold with miraculous promises, as in the case of the multi-level marketing company. <em>bHIP Global<\/em>. The biosafety rule is simple: no over-the-counter supplement should be used to consistently exceed the labeled dosage without medical supervision.<\/p>\n\n<h2>Balance \/ Conclusions<\/h2>\n<p><strong>First<\/strong>, Vitamin D is no longer just a matter of bone health. It is a prohormone with systemic effects\u2014immune, muscular, metabolic\u2014and ensuring sufficient intake is a public health objective, not a whim of well-being.<\/p>\n<p><strong>Second<\/strong>, In Mexico, the deficiency is massive and paradoxical: it affects urban areas and high-income earners more than rural areas, diet alone is insufficient to correct it, and only the measurement of 25(OH)D reveals the true extent of the problem. Abundant sunshine guarantees nothing when life is spent indoors.<\/p>\n<p><strong>Third<\/strong>, Rational supplementation is individualized and, increasingly, triadic: quality vitamin D3, magnesium that activates it and vitamin K2 that directs calcium to the bone and away from the artery, taken with fat to be absorbed.<\/p>\n<p><strong>Room<\/strong>, The ethical limit is prudence. Hypercalcemia, nephropathies, and especially sarcoidosis necessitate avoiding blind supplementation: correcting without measuring, in the wrong patient, can transform a cheap remedy into preventable harm.<\/p>\n\n<div class=\"mm-refs\"><h3>Selected references<\/h3><ol>\n<li>Public Health of Mexico \/ INSP. <em>Vitamin D status in Mexican women at reproductive age, ENSANUT 2018-2019.<\/em> SciELO.<\/li>\n<li>Medical Research Unit in Nutrition (IMSS). <em>Vitamin D deficiency in Mexico: positioning.<\/em> IMSS Medical Journal.<\/li>\n<li>National Institute of Public Health. <em>Micronutrient status in Mexican children and women: ENSANUT Continua 2022.<\/em><\/li>\n<li>National Institutes of Health, Office of Dietary Supplements. <em>Facts about vitamin D.<\/em> NIH.<\/li>\n<li>World Medical Association (WMA). <em>Statement on Vitamin D Deficiency.<\/em><\/li>\n<li>Mexican Social Security Institute. <em>Clinical Practice Guideline (CPG) on vitamin D.<\/em> IMSS.<\/li>\n<li>General and Family Medicine. <em>Update on the treatment with cholecalciferol in hypovitaminosis D from primary care.<\/em><\/li>\n<li>MSD Manual, Consumer Version. <em>Excess vitamin D.<\/em><\/li>\n<li>MedlinePlus. <em>Hypervitaminosis D.<\/em> U.S. National Library of Medicine.<\/li>\n<li>PMC \/ NCBI. <em>Vitamin D status in sarcoidosis: a cross-sectional study.<\/em><\/li>\n<li>PMC \/ NCBI. <em>The role of vitamin D in sarcoidosis.<\/em><\/li>\n<li>AEMPS, CIMA. <em>Cholecalciferol 50,000 IU technical sheet.<\/em><\/li>\n<li>Murciasalud, Preevid. <em>Daily or bi-weekly doses for pregnant women with vitamin D deficiency.<\/em><\/li>\n<li>COFEPRIS. <em>Health alert regarding products from the company bHIP Global.<\/em><\/li>\n<\/ol><\/div>\n\n<\/div>","protected":false},"excerpt":{"rendered":"<p>VITAMINA D: ANATOM\u00cdA DE UNA CARENCIA Metabolismo, el d\u00e9ficit silencioso en M\u00e9xico y la suplementaci\u00f3n basada en evidencia Nota editorial. Este dossier es una revisi\u00f3n de literatura cl\u00ednica, farmacol\u00f3gica y de epidemiolog\u00eda nutricional. No constituye consejo m\u00e9dico ni una invitaci\u00f3n a la automedicaci\u00f3n. La suplementaci\u00f3n con vitamina D \u2014sobre todo en dosis altas\u2014 puede interactuar [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":909,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[51,45],"tags":[],"class_list":["post-907","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-longevidad-metricas","category-noticias"],"acf":{"hallazgo_clave":"El 78% de las mujeres mexicanas en edad reproductiva no alcanza suficiencia de vitamina D pese al sol abundante.","tiempo_lectura":13,"nivel_evidencia":"alto","fuente_original":"https:\/\/www.scielo.org.mx\/scielo.php?script=sci_arttext&pid=S0036-36342021000300394","protocolo_aplicable":true,"referencias_texto":"","tags_cientificos":"vitamina D, colecalciferol, 25-hidroxivitamina D, calcitriol, vitamina K2, magnesio, ENSANUT, hipovitaminosis D, sarcoidosis, COFEPRIS"},"hallazgo_clave":"El 78% de las mujeres mexicanas en edad reproductiva no alcanza suficiencia de vitamina D pese al sol abundante.","tiempo_lectura":"13","nivel_evidencia":"alto","fuente_original":"https:\/\/www.scielo.org.mx\/scielo.php?script=sci_arttext&pid=S0036-36342021000300394","protocolo_aplicable":true,"referencias_texto":null,"tags_cientificos":"vitamina D, colecalciferol, 25-hidroxivitamina D, calcitriol, vitamina K2, magnesio, ENSANUT, hipovitaminosis D, sarcoidosis, COFEPRIS","_links":{"self":[{"href":"https:\/\/menteymanzana.com\/en\/wp-json\/wp\/v2\/posts\/907","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/menteymanzana.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/menteymanzana.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/menteymanzana.com\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/menteymanzana.com\/en\/wp-json\/wp\/v2\/comments?post=907"}],"version-history":[{"count":2,"href":"https:\/\/menteymanzana.com\/en\/wp-json\/wp\/v2\/posts\/907\/revisions"}],"predecessor-version":[{"id":914,"href":"https:\/\/menteymanzana.com\/en\/wp-json\/wp\/v2\/posts\/907\/revisions\/914"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/menteymanzana.com\/en\/wp-json\/wp\/v2\/media\/909"}],"wp:attachment":[{"href":"https:\/\/menteymanzana.com\/en\/wp-json\/wp\/v2\/media?parent=907"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/menteymanzana.com\/en\/wp-json\/wp\/v2\/categories?post=907"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/menteymanzana.com\/en\/wp-json\/wp\/v2\/tags?post=907"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}